Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.44 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954989 | 0.95 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL7956488 | 0.93 | MAPT (0.49) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL7954386 | 0.91 | L3MBTL1 (0.49) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL7954895 | 0.84 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL7959737 | 0.83 | L3MBTL1 (0.56) | CYP1A2CYP2C19L3MBTL1MAPTATM | |
| SCHEMBL27575303 | 0.82 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL3199017 | 0.81 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL9689273 | 0.81 | L3MBTL1 (0.69) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL919038 | 0.79 | CYP1A2 (0.58) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT | |
| SCHEMBL7999552 | 0.79 | PPARD (0.60) | CYP1A2CYP2C9CYP2C19L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |