Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956488 | 0.98 | MAPT (0.49) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL7954892 | 0.95 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL7954386 | 0.89 | L3MBTL1 (0.49) | CYP1A2CYP2C9CYP2C19MAPTHTR2B | |
| SCHEMBL7954993 | 0.84 | L3MBTL1 (0.49) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL7956489 | 0.83 | MAPT (0.50) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL677508 | 0.82 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL7959737 | 0.82 | L3MBTL1 (0.56) | CYP1A2CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL2924592 | 0.81 | MAPT (0.51) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL677597 | 0.81 | MAPT (0.51) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL17309906 | 0.81 | MAPT (0.51) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |