Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 12/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478188 | 0.87 | HRH1 (0.42) | HRH1KDM4EALDH1A1 | |
| SCHEMBL7473747 | 0.87 | HRH1 (0.41) | HRH1KDM4EALDH1A1 | |
| SCHEMBL7471446 | 0.87 | HRH1 (0.42) | HRH1KDM4EALDH1A1 | |
| SCHEMBL7466438 | 0.83 | HRH1 (0.54) | HRH1KDM4EALDH1A1 | |
| SCHEMBL9695580 | 0.82 | POLB (0.60) | HRH1KDM4EALDH1A1 | |
| SCHEMBL9267715 | 0.82 | HRH1 (0.53) | HRH1KDM4EKCNH2CHRM1 | |
| SCHEMBL9260913 | 0.81 | HRH1 (0.51) | HRH1KDM4EKCNH2CHRM1 | |
| Bromide SCHEMBL3553550 | 0.81 | POLB (0.59) | HRH1KDM4EALDH1A1 | |
| SCHEMBL9260555 | 0.81 | HRH1 (0.65) | HRH1 | |
| SCHEMBL9260920 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |
| US-5380731-A | Antiallergic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0561973-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010491-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-25 | — | — | WO | disclosed |