Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473405 | 0.90 | HRH1 (0.44) | HRH1NOD2NOD1STS | |
| SCHEMBL7477117 | 0.89 | NOD2 (0.42) | HRH1NOD2NOD1STS | |
| SCHEMBL13317058 | 0.87 | KDM4E (0.54) | HRH1KDM4ENOD2NOD1STS | |
| SCHEMBL7473715 | 0.86 | HRH1 (0.55) | HRH1NOD2NOD1STS | |
| SCHEMBL992547 | 0.86 | HRH1 (0.66) | HRH1KDM4EKCNH2CHRM1 | |
| SCHEMBL7899281 | 0.84 | HRH1 (0.54) | HRH1NOD2NOD1STS | |
| SCHEMBL7479016 | 0.84 | NOD2 (0.45) | HRH1KDM4ENOD2NOD1STS | |
| SCHEMBL9266382 | 0.83 | NOD2 (0.43) | HRH1KDM4ENOD2NOD1STS | |
| SCHEMBL9258336 | 0.82 | NOD2 (0.42) | HRH1KDM4ENOD2NOD1STS | |
| SCHEMBL7954906 | 0.81 | HRH1 (0.52) | HRH1KDM4EKCNH2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380731-A | Antiallergic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0561973-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010491-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-25 | — | — | WO | disclosed |