Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7887857 | 0.86 | HTR3A (0.52) | KDM4E | |
| SCHEMBL9695580 | 0.86 | POLB (0.60) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9260978 | 0.85 | KDM4E (0.50) | KDM4EHSD17B10APEX1ALDH1A1HPGD | |
| Bromide SCHEMBL3553550 | 0.85 | POLB (0.59) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7468259 | 0.83 | HTR3A (0.54) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7470479 | 0.81 | HRH1 (0.50) | KDM4EHSD17B10 | |
| SCHEMBL7474308 | 0.81 | HRH1 (0.62) | — | |
| SCHEMBL7469554 | 0.80 | HRH1 (0.49) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL7954906 | 0.80 | HRH1 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL7465508 | 0.79 | HRH1 (0.41) | ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389634-A | Treating arterial hypertension, relaxing uterus, prevention of post-angioplastic restenosis | ROUSSEL-UCLAF (FR) | 1995-02-14 | — | — | US | disclosed |
| US-5380731-A | Antiallergic compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-10 | — | — | US | disclosed |
| EP-0561973-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010491-A1 | ANTIALLERGIC COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-25 | — | — | WO | disclosed |