Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.33 |
| ▸ | PYGM | P11217 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716130 | 0.84 | SMYD3 (0.52) | SMYD3MTNR1AMASP2F2GAA | |
| SCHEMBL23275075 | 0.84 | MTNR1A (0.46) | SMYD3MTNR1AMASP2F2GAA | |
| SCHEMBL20870877 | 0.75 | PDPK1 (0.46) | SMYD3MTNR1AGAAMAPTMTNR1B | |
| SCHEMBL8568355 | 0.72 | MTNR1A (0.50) | SMYD3MTNR1AGAAMTNR1BCA1 | |
| SCHEMBL8568363 | 0.72 | MTNR1A (0.50) | SMYD3MTNR1AGAAMTNR1BCA1 | |
| SCHEMBL8568359 | 0.72 | MTNR1A (0.50) | SMYD3MTNR1AGAAMTNR1BCA1 | |
| SCHEMBL10310232 | 0.69 | PDPK1 (0.56) | CA1CA2 | |
| SCHEMBL29433039 | 0.69 | MTNR1A (0.61) | MTNR1AMTNR1BCA1CA2PLAU | |
| SCHEMBL1520715 | 0.69 | PDPK1 (0.56) | CA1CA2 | |
| SCHEMBL29433082 | 0.69 | MTNR1A (0.61) | MTNR1AMTNR1BCA1CA2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6174924-B1 | Therapeutic guanidines | CAMBRIDGE NEUROSCIENCE, INC. | 2001-01-16 | — | — | US | disclosed |