Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871627 | 0.90 | MAPT (0.40) | LIPGL3MBTL1MAPTTHRBKMT2A | |
| SCHEMBL5871823 | 0.85 | MAPT (0.42) | L3MBTL1MAPTTHRBKMT2AALDH1A1 | |
| SCHEMBL5871987 | 0.84 | MAPT (0.48) | L3MBTL1MAPTTHRBRXFP1ALDH1A1 | |
| SCHEMBL7954712 | 0.84 | PDE4A (0.48) | L3MBTL1MAPTTHRBKMT2ARXFP1 | |
| SCHEMBL7955057 | 0.79 | PDE4A (0.51) | MAPTTHRBKMT2ARXFP1 | |
| SCHEMBL5872271 | 0.78 | MAPT (0.41) | L3MBTL1MAPTTHRBKMT2AALDH1A1 | |
| SCHEMBL7954380 | 0.77 | RXFP1 (0.52) | MAPTTHRBKMT2ARXFP1ALDH1A1 | |
| SCHEMBL5871382 | 0.77 | LIPG (0.37) | LIPGL3MBTL1THRBKMT2ASYK | |
| SCHEMBL5871439 | 0.77 | LIPG (0.43) | LIPGL3MBTL1MAPTTHRBKMT2A | |
| SCHEMBL9709087 | 0.74 | KMT2A (0.50) | LIPGL3MBTL1MAPTTHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | claimed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | claimed |
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |