Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954712 | 0.88 | PDE4A (0.48) | RXFP1MAPTPTGDR2TP53THRB | |
| SCHEMBL7955057 | 0.82 | PDE4A (0.51) | RXFP1MAPTPTGDR2TP53THRB | |
| SCHEMBL7955076 | 0.77 | LIPG (0.42) | RXFP1MAPTTHRBKMT2AALDH1A1 | |
| SCHEMBL28969557 | 0.70 | MAPT (0.58) | RXFP1MAPTPTGDR2TP53THRB | |
| SCHEMBL5871823 | 0.70 | MAPT (0.42) | MAPTPTGDR2THRBMEN1KMT2A | |
| SCHEMBL2087811 | 0.69 | PTGDR2 (0.58) | RXFP1MAPTPTGDR2TP53MEN1 | |
| SCHEMBL5871987 | 0.68 | MAPT (0.48) | RXFP1MAPTPTGDR2TP53THRB | |
| SCHEMBL5871627 | 0.67 | MAPT (0.40) | RXFP1MAPTTP53THRBKMT2A | |
| SCHEMBL7956548 | 0.66 | AURKA (0.46) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL24914454 | 0.64 | RXFP1 (0.52) | RXFP1MAPTPTGDR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |