Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220937 | 0.83 | IAPP (0.55) | TAAR1AOC3MAOBMPOCASP3 | |
| SCHEMBL31182394 | 0.83 | TAAR1 (0.52) | TAAR1AOC3MAOBMPOIDO1 | |
| Acetic Acid SCHEMBL29114584 | 0.80 | MEN1 (0.54) | TAAR1MAOBACKR3MEN1ALDH1A1 | |
| SCHEMBL7331602 | 0.78 | TAAR1 (0.56) | TAAR1AOC3MAOBMPOCASP3 | |
| SCHEMBL8526001 | 0.78 | TAAR1 (0.75) | TAAR1AOC3MAOBMPOIDO1 | |
| SCHEMBL435759 | 0.77 | TAAR1 (0.48) | TAAR1AOC3MAOBIDO1ALDH1A1 | |
| SCHEMBL6964948 | 0.77 | TAAR1 (0.54) | TAAR1AOC3MAOBMPOCASP3 | |
| SCHEMBL29444401 | 0.77 | MEN1 (0.59) | TAAR1CASP3CASP7MEN1ALDH1A1 | |
| SCHEMBL246473 | 0.77 | MEN1 (0.59) | TAAR1CASP3CASP7MEN1ALDH1A1 | |
| SCHEMBL6601966 | 0.76 | TAAR1 (0.48) | TAAR1AOC3MAOBMPOCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274602-B1 | ADMINISTERING COMPOSTITIONS SUCH AS 3,3-DIMETHYL-1-((2S)-2-(5-(3-PYRIDYL) PENTANOYL)-1-PYRROLIDINE)-1, 2-PENTANEDIONE TO TREAT ALOPECIA OR PROMOTING HAIR GROWTH IN ANIMALS | GPI NIL HOLDINGS, INC. | 2001-08-14 | — | — | US | disclosed |