Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 12/20 | 0.80 |
| ▸ | PTGER4 | P35408 | 11/20 | 0.80 |
| ▸ | PTGER2 | P43116 | 11/20 | 0.80 |
| ▸ | PTGER1 | P34995 | 8/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961860 | 1.00 | PTGER3 (0.80) | PTGER3PTGER4PTGER2PTGER1PTGDR | |
| SCHEMBL7798340 | 0.89 | PTGER3 (1.00) | PTGER3PTGER4PTGER2PTGER1PTGDR | |
| SCHEMBL7798336 | 0.89 | PTGER3 (1.00) | PTGER3PTGER4PTGER2PTGER1PTGDR | |
| SCHEMBL7947922 | 0.86 | PTGER3 (0.82) | PTGER3PTGER4PTGER2PTGER1PTGDR | |
| SCHEMBL7805997 | 0.81 | PTGER4 (0.73) | PTGER3PTGER4PTGER2PTGER1 | |
| SCHEMBL7961865 | 0.80 | PTGER4 (0.69) | PTGER3PTGER4PTGER2PTGER1ALOX5 | |
| SCHEMBL2391059 | 0.77 | PTGER4 (0.50) | PTGER3PTGER4PTGER2PTGER1ALOX5 | |
| SCHEMBL24611344 | 0.77 | THRA (0.48) | PTGER3PTGER4PTGER2ALOX5LMNA | |
| SCHEMBL7807171 | 0.76 | PTGER4 (0.73) | PTGER3PTGER4PTGER2PTGER1L3MBTL1 | |
| SCHEMBL7955267 | 0.76 | PTGER4 (1.00) | PTGER3PTGER4PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |