Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CTSV | O60911 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957505 | 0.87 | NT5E (0.47) | NT5EHTTMAPTLMNAALDH1A1 | |
| SCHEMBL7959152 | 0.87 | NT5E (0.55) | NT5EHTTALDH1A1 | |
| SCHEMBL7957838 | 0.87 | NT5E (0.47) | NT5EHTTMAPTALDH1A1NPC1 | |
| SCHEMBL7948147 | 0.83 | ALDH1A1 (0.38) | HTTMAPTLMNAALDH1A1NPC1 | |
| SCHEMBL7955551 | 0.83 | NT5E (0.45) | NT5EHTTMAPTALDH1A1NPC1 | |
| SCHEMBL7957730 | 0.82 | NT5E (0.47) | NT5EHTTMAPTLMNAALDH1A1 | |
| SCHEMBL7958119 | 0.81 | NT5E (0.54) | NT5EALDH1A1 | |
| SCHEMBL7957443 | 0.81 | NT5E (0.42) | NT5EHTTMAPTALDH1A1NPC1 | |
| SCHEMBL7149762 | 0.79 | SSTR1 (0.42) | MAPTMEN1KMT2ACYP2C19 | |
| SCHEMBL1491856 | 0.78 | TACR1 (0.35) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |
| CN-1185786-A | Sugar-modified cytostatics | BAYER AG (DE) | 1998-06-24 | — | — | CN | disclosed |