Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.35 |
| ▸ | CDC25B | P30305 | 4/20 | 0.35 |
| ▸ | GJB2 | P29033 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958119 | 0.94 | NT5E (0.54) | NT5EALDH1A1CA1CA2CA9 | |
| SCHEMBL7957838 | 0.93 | NT5E (0.47) | NT5EALDH1A1SSTR1SSTR2SSTR4 | |
| SCHEMBL7957505 | 0.90 | NT5E (0.47) | NT5EALDH1A1HTT | |
| SCHEMBL7955551 | 0.89 | NT5E (0.45) | NT5EALDH1A1SSTR1SSTR2SSTR4 | |
| SCHEMBL11886555 | 0.88 | SSTR1 (0.40) | NT5EALDH1A1SSTR1SSTR2SSTR4 | |
| SCHEMBL7955324 | 0.87 | NT5E (0.43) | NT5EALDH1A1HTT | |
| SCHEMBL7948307 | 0.85 | NT5E (0.64) | NT5ECA1CA2CA9SSTR1 | |
| SCHEMBL7948306 | 0.85 | NT5E (0.64) | NT5ECA1CA2CA9SSTR1 | |
| SCHEMBL7955867 | 0.83 | NT5E (0.61) | NT5ESSTR4PTPN1CDC25BGJB2 | |
| SCHEMBL7955866 | 0.83 | NT5E (0.61) | NT5ESSTR4PTPN1CDC25BGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |