SCHEMBL7955396

SCHEMBL7955396

COC(=O)CCc1ccc(O)c(C(C)(C)Cn2nc3ccc(C(F)(F)F)cc3n2)c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.38
IDH1 O75874 2/20 0.37
MCHR1 Q99705 6/20 0.36
CNR1 P21554 2/20 0.35
CNR2 P34972 2/20 0.35
APP P05067 1/20 0.35
GCGR P47871 2/20 0.34
PPARA Q07869 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PTPN1 P18031 1/20 0.34
FFAR1 O14842 1/20 0.34
FFAR2 O15552 1/20 0.34
PPARD Q03181 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5835348 0.87 KDM4E (0.41) APPKDM4EPTPN1
SCHEMBL5693442 0.81 FFAR4 (0.40) FFAR4IDH1MCHR1PPARAKDM4E
SCHEMBL29353898 0.76 GAA (0.41) IDH1MCHR1
SCHEMBL768820 0.76 GAA (0.41) IDH1MCHR1
SCHEMBL135249 0.75 FFAR1 (0.40) FFAR4FFAR1
SCHEMBL14462662 0.75 PPARA (0.45) FFAR4IDH1PPARAKDM4EFFAR1
SCHEMBL3416177 0.74 APP (0.43) APPKDM4E
SCHEMBL27381689 0.73 ALOX5 (0.46) CNR1CNR2APPPTPN1
SCHEMBL13546033 0.73 KDM4E (0.35) IDH1MCHR1KDM4E
SCHEMBL7523053 0.73 KDM4E (0.35) IDH1MCHR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271377-B1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2001-08-07 US disclosed