Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 15/20 | 0.50 |
| ▸ | FEN1 | P39748 | 15/20 | 0.50 |
| ▸ | PARG | Q86W56 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058096 | 0.81 | ALOX5AP (0.56) | ALOX5APFEN1 | |
| SCHEMBL3833442 | 0.81 | NSD2 (0.61) | ALOX5APFEN1PARGNSD2 | |
| SCHEMBL2803354 | 0.80 | NSD2 (0.58) | ALOX5APFEN1PARGNSD2KDM4E | |
| SCHEMBL1968159 | 0.80 | ALOX5AP (0.59) | ALOX5APFEN1PARGNSD2 | |
| SCHEMBL8831875 | 0.78 | ALOX5AP (0.47) | ALOX5APFEN1PARGNSD2 | |
| SCHEMBL6628076 | 0.76 | ALOX5AP (0.59) | ALOX5APFEN1 | |
| SCHEMBL7247915 | 0.76 | ALOX5AP (0.46) | ALOX5APFEN1PARGNSD2 | |
| SCHEMBL3830116 | 0.76 | NSD2 (0.59) | ALOX5APFEN1PARGNSD2 | |
| SCHEMBL5885311 | 0.75 | ALOX5AP (0.58) | ALOX5APFEN1 | |
| SCHEMBL890585 | 0.75 | ALOX5AP (0.65) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207697-B1 | AMIDINYL-SUBSTITUTED RINGS; ANTICOAGULANTS; THROMBOEMBOLIC DISORDERS; ANTIISCHEMIC AND ANTIINFLAMMATORY AGENTS; STROKES; SERINE PROTEASE INHIBITORS | DUPONT PHARMACEUTICALS COMPANY | 2001-03-27 | — | — | US | disclosed |