SCHEMBL4058096

SCHEMBL4058096

CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 20/20 0.56
FEN1 P39748 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6308004 0.86 ALOX5AP (0.56) ALOX5APFEN1
SCHEMBL1111509 0.85 NSD2 (0.50) ALOX5APFEN1
SCHEMBL15924548 0.82 FEN1 (0.54) ALOX5APFEN1
SCHEMBL7955567 0.81 ALOX5AP (0.50) ALOX5APFEN1
SCHEMBL3833442 0.79 NSD2 (0.61) ALOX5APFEN1
SCHEMBL2803354 0.79 NSD2 (0.58) ALOX5APFEN1
SCHEMBL24429391 0.79 NSD2 (0.51) ALOX5APFEN1
SCHEMBL1968159 0.79 ALOX5AP (0.59) ALOX5APFEN1
SCHEMBL9122272 0.79 ALOX5AP (0.65) ALOX5APFEN1
SCHEMBL3831543 0.78 ALOX5AP (0.60) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1582274-B Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade WARNER LAMBERT CO 2011-03-09 CN disclosed
EP-1824826-A4 ARYL SULFONIC PYRIDOXINES AS ANTIPLATELET AGENTS MEDICURE INT INC (BB) 2009-06-03 EP disclosed
EP-1824826-A1 ARYL SULFONIC PYRIDOXINES AS ANTIPLATELET AGENTS Medicure International Inc. (BB) 2007-08-29 EP disclosed
WO-2006045204-A1 ARYL SULFONIC PYRIDOXINES AS ANTIPLATELET AGENTS MEDICURE INTERNATIONAL INC. (CA) 2006-05-04 WO disclosed
CN-1582274-A Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade WARNER LAMBERT CO (US) 2005-02-16 CN disclosed