Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934880 | 1.00 | DPP4 (0.46) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL2374243 | 0.80 | DPP4 (0.50) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL795585 | 0.80 | DPP4 (0.37) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL795583 | 0.80 | DPP4 (0.37) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL31028945 | 0.77 | MEN1 (0.41) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL1101279 | 0.76 | DPP4 (0.41) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL8613849 | 0.75 | MEN1 (0.39) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL692130 | 0.75 | MEN1 (0.39) | DPP4F2ADRA2AADRA2CLMNA | |
| SCHEMBL20312145 | 0.74 | CYP1A2 (0.52) | DPP4F2LMNAALDH1A1 | |
| SCHEMBL2398534 | 0.73 | MEN1 (0.38) | DPP4F2ADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106399-A2 | PROCESS FOR PREPARING N-PROTECTED β-AMINO ALDEHYDE COMPOUNDS | THERAVANCE, INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| US-6313139-B1 | ADMINISTERING BENZYLAMINE DERIVATIVE FOR THERAPY OF PSYCHIATRIC DISORDER IN MAMMALS | AKZO NOBEL N. V. (NL) | 2001-11-06 | — | — | US | disclosed |