Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.71 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.71 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.71 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.71 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.71 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.71 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.71 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.71 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.71 |
| ▸ | DAO | P14920 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356582 | 0.83 | GRIN2D (0.63) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7355341 | 0.83 | GRIN2D (0.63) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7350271 | 0.83 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7356050 | 0.83 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7349363 | 0.83 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7357397 | 0.83 | GRIA2 (0.59) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7360391 | 0.80 | GRIA1 (0.59) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7350441 | 0.80 | GRIN2D (0.58) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8915313 | 0.80 | DAO (0.47) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL7350733 | 0.79 | GRIN2D (0.57) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288065-B1 | CENTRAL NERVOUS SYSTEM DISORDERS; PARKINSON*S AND ALZHEIMER*S DISEASE | SCHERING AKTIENGESEELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| WO-1993008173-A1 | QUINOXALINE DERIVATES WITH AFFINITY FOR QUISQUALATE-RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-29 | — | — | WO | disclosed |