Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 6/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 6/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 6/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955880 | 0.80 | GRIA1 (0.71) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL24335125 | 0.80 | DAO (0.47) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL29580445 | 0.80 | DAO (0.47) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7359339 | 0.77 | GRIA1 (0.57) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9365003 | 0.76 | DAO (0.70) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL14326956 | 0.72 | KMT2A (0.62) | DAOGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8915220 | 0.72 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8564331 | 0.70 | TP53 (0.68) | DAO | |
| SCHEMBL10169863 | 0.70 | KMT2A (0.55) | DAOGRIN1GRIN2BKDM4EALDH1A1 | |
| SCHEMBL8348807 | 0.69 | DAO (0.59) | DAOGRIN1GRIN2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654303-A | FOR TREATING NERVOUS SYSTEM OR CARDIOVASCULAR SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 1997-08-05 | — | — | US | disclosed |