Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TACR2 | P21452 | 3/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.51 |
| ▸ | HRH1 | P35367 | 2/20 | 0.51 |
| ▸ | TACR3 | P29371 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958328 | 0.92 | TACR2 (0.53) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL7947406 | 0.91 | PKM (0.52) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL7947283 | 0.91 | TACR2 (0.57) | ALDH1A1TACR2TACR1HRH1TACR3 | |
| SCHEMBL7958307 | 0.90 | TACR2 (0.55) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL6997708 | 0.90 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1TACR2TACR1HRH1 | |
| SCHEMBL7958490 | 0.89 | HRH1 (0.52) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL7947243 | 0.89 | TACR2 (0.45) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL7947581 | 0.89 | TACR2 (0.51) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL7954948 | 0.89 | TACR2 (0.64) | TACR2TACR1HRH1TACR3 | |
| SCHEMBL8641331 | 0.89 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1TACR2TACR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329392-B1 | ANTIALLERGENS | AVENTIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |
| EP-0777666-B1 | SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |