Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5398264 | 0.97 | NPY5R (0.71) | NPY5R | |
| Hydrochloric Acid SCHEMBL5398595 | 0.97 | NPY5R (0.71) | NPY5R | |
| Hydrochloric Acid SCHEMBL5388828 | 0.96 | NPY5R (0.72) | NPY5R | |
| SCHEMBL14408700 | 0.84 | NPY5R (0.82) | NPY5R | |
| SCHEMBL1594283 | 0.83 | NPY5R (0.98) | NPY5R | |
| SCHEMBL14408693 | 0.82 | NPY5R (1.00) | NPY5R | |
| SCHEMBL1594047 | 0.82 | NPY5R (1.00) | NPY5R | |
| SCHEMBL14408682 | 0.81 | NPY5R (0.77) | NPY5R | |
| SCHEMBL1593364 | 0.81 | NPY5R (0.61) | NPY5R | |
| SCHEMBL14408719 | 0.81 | NPY5R (1.00) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225330-B1 | Selective NPY (Y5) antagonists (tricyclics) | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-05-01 | — | — | US | disclosed |