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Sugi Predict / Compounds / SCHEMBL7956402

SCHEMBL7956402

SCHEMBL7956402

Cc1ccc2cccc(OCc3c(Cl)ccc(S(=O)(=O)N4CCC[C@H]4C(=O)NC4CCN(C(=O)CCN(C=NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)CC4)c3Cl)c2n1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 12/20 0.51
▸ BDKRB2 P30411 8/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7815251 0.97 BDKRB2 (0.50) RORCBDKRB2
SCHEMBL7812531 0.96 RORC (0.51) RORCBDKRB2
SCHEMBL7814458 0.92 RORC (0.57) RORCBDKRB2
SCHEMBL7815139 0.90 BDKRB2 (0.54) RORCBDKRB2
SCHEMBL7818233 0.89 RORC (0.55) RORCBDKRB2
SCHEMBL7814911 0.89 RORC (0.55) RORCBDKRB2
SCHEMBL7811150 0.88 BDKRB2 (0.55) RORCBDKRB2
SCHEMBL7945797 0.88 BDKRB2 (0.54) RORCBDKRB2
SCHEMBL7805316 0.88 RORC (0.54) RORCBDKRB2
SCHEMBL7814262 0.88 RORC (0.58) RORCBDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6211181-B1 ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIALLERGENS, AND ANTIASTHMATICS FOURNIER INDUSTRIE ET SANTE (FR) 2001-04-03 — — US disclosed