Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.48 |
| ▸ | PTAFR | P25105 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954984 | 0.88 | SLC29A1 (0.53) | TSHRCYP2D6ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14216877 | 0.86 | ALDH1A1 (0.64) | TSHRCYP2D6KDM4EALDH1A1TDP1 | |
| SCHEMBL3435152 | 0.86 | ALDH1A1 (0.58) | TSHRCYP2D6KDM4EALDH1A1TDP1 | |
| SCHEMBL30462836 | 0.86 | ALDH1A1 (0.64) | TSHRCYP2D6KDM4EALDH1A1TDP1 | |
| SCHEMBL8890102 | 0.85 | TSHR (0.54) | TSHRCYP2D6KDM4EALDH1A1SYK | |
| Hydrochloric Acid SCHEMBL5692430 | 0.85 | ALDH1A1 (0.63) | TSHRCYP2D6KDM4EALDH1A1TDP1 | |
| SCHEMBL7959655 | 0.84 | TSHR (0.60) | TSHRCYP2D6KDM4EALDH1A1HPGD | |
| SCHEMBL4036604 | 0.84 | CYP2D6 (0.60) | TSHRCYP2D6KDM4EALDH1A1SYK | |
| SCHEMBL17921473 | 0.80 | HTR1A (0.52) | TSHRCYP2D6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4056455 | 0.80 | ALDH1A1 (0.59) | TSHRKDM4EALDH1A1SYKTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297274-B1 | SUBSTITUTED 5-HYDROXYFURANONES | WARNER-LAMBERT COMPANY | 2001-10-02 | — | — | US | disclosed |