Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.43 |
| ▸ | RELA | Q04206 | 3/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956850 | 0.90 | GPR55 (0.52) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL5736045 | 0.74 | HTR7 (0.63) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL28925303 | 0.68 | SMN1; SMN2 (0.77) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL7958685 | 0.68 | NR1H4 (0.62) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7958856 | 0.68 | HTR7 (0.62) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL17226529 | 0.68 | SLC2A1 (0.71) | ALDH1A1SLC2A1TLR9NCF1KDM4E | |
| SCHEMBL7957222 | 0.68 | HTR7 (0.53) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL4933326 | 0.67 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL7956454 | 0.67 | HTR7 (0.52) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 | |
| Irampanel SCHEMBL678128 | 0.67 | HTR7 (0.63) | RAB9ANPC1SMN1; SMN2TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |