Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582390 | 0.83 | BACE1 (0.52) | CXCR3BACE1 | |
| SCHEMBL4911761 | 0.82 | CXCR3 (0.52) | CXCR3 | |
| SCHEMBL14647093 | 0.79 | BACE1 (0.58) | CXCR3BACE1 | |
| SCHEMBL8436783 | 0.77 | TP53 (0.64) | CXCR3TP53 | |
| SCHEMBL12621038 | 0.75 | SPPL2A (0.54) | — | |
| SCHEMBL9287153 | 0.75 | RORC (0.68) | CXCR3BACE1 | |
| SCHEMBL11988980 | 0.75 | SPPL2A (0.75) | — | |
| SCHEMBL1804868 | 0.74 | SPPL2A (0.60) | — | |
| SCHEMBL6099960 | 0.74 | SPPL2A (0.60) | — | |
| SCHEMBL1804866 | 0.74 | SPPL2A (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6169085-B1 | A VIRICIDE FOR PREVENTING AND TREATING RETROVIRAL INFECTION OR THE SPREAD OF A RETROVIRUS, INHIBITING REPLICATION OF A RETROVIRUS AND TREATING AIDS | G. D. SEARLE & COMPANY | 2001-01-02 | — | — | US | disclosed |