Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954876 | 0.89 | SMN1; SMN2 (0.55) | HTR7GRM5S1PR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7957222 | 0.89 | HTR7 (0.53) | HTR7S1PR1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5736045 | 0.88 | HTR7 (0.63) | HTR7S1PR1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7947853 | 0.88 | HTR7 (0.51) | HTR7GRM5S1PR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7947522 | 0.88 | HTR7 (0.51) | HTR7S1PR1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7954897 | 0.84 | HTR7 (0.56) | HTR7SMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL7956454 | 0.83 | HTR7 (0.52) | HTR7S1PR1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7955292 | 0.83 | TTR (0.55) | HTR7S1PR1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL7962019 | 0.82 | NPC1 (0.56) | HTR7SMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL7947658 | 0.82 | SMN1; SMN2 (0.56) | HTR7S1PR1SMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |