Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.56 |
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964562 | 0.96 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL7954897 | 0.92 | HTR7 (0.56) | NPC1RAB9ASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL7956815 | 0.88 | HTR7 (0.66) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL7947650 | 0.88 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL7957222 | 0.86 | HTR7 (0.53) | NPC1RAB9ASMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL7957242 | 0.86 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7957127 | 0.86 | CASP3 (0.57) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5736045 | 0.86 | HTR7 (0.63) | NPC1RAB9ASMN1; SMN2L3MBTL1HTR7 | |
| SCHEMBL7955292 | 0.85 | TTR (0.55) | NPC1RAB9ASMN1; SMN2GAAKMT2A | |
| SCHEMBL7960663 | 0.85 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |