Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428833 | 0.80 | SMN1; SMN2 (0.62) | KMT2ARAB9ANPC1MAPTTSHR | |
| SCHEMBL7961699 | 0.78 | SMN1; SMN2 (0.81) | KMT2ARAB9ANPC1MAPTTSHR | |
| SCHEMBL7947720 | 0.76 | MAPT (0.59) | KMT2ARAB9ANPC1MAPTTSHR | |
| SCHEMBL12171135 | 0.75 | SMN1; SMN2 (0.70) | KMT2ARAB9ANPC1MAPTTSHR | |
| SCHEMBL23288081 | 0.75 | NPC1 (0.64) | KMT2ARAB9ANPC1MAPTTSHR | |
| SCHEMBL29728586 | 0.75 | NCEH1 (0.54) | RAB9ANPC1TSHRLMNAPKM | |
| SCHEMBL16965297 | 0.75 | NCEH1 (0.54) | RAB9ANPC1TSHRLMNAPKM | |
| SCHEMBL7961394 | 0.75 | NPSR1 (0.59) | KMT2ARAB9ANPC1MAPTTSHR | |
| SCHEMBL11735128 | 0.75 | NPC1 (0.68) | KMT2ARAB9ANPC1MAPTTSHR | |
| Irampanel SCHEMBL678128 | 0.74 | HTR7 (0.63) | KMT2ARAB9ANPC1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277872-B1 | ANTIISCHEMIC AGENTS; BRAIN DISORDERS | BOEHRINGER INGELHEIM KG (DE) | 2001-08-21 | — | — | US | disclosed |