Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23512479 | 1.00 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| SCHEMBL7957004 | 1.00 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| SCHEMBL309763 | 0.94 | HCAR2 (0.59) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| SCHEMBL765933 | 0.94 | HCAR2 (0.59) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| Bicarbonate SCHEMBL867321 | 0.93 | HCAR2 (0.57) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| Hydrochloric Acid SCHEMBL11763321 | 0.93 | HCAR2 (0.57) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| SCHEMBL7966311 | 0.86 | KDM4E (0.70) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| SCHEMBL7966308 | 0.86 | KDM4E (0.70) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| Methacrylic Acid SCHEMBL10714814 | 0.85 | HCAR2 (0.49) | KDM4ESMN1; SMN2ALDH1A1HPGDMITF | |
| SCHEMBL4946176 | 0.84 | HCAR2 (0.71) | KDM4ESMN1; SMN2ALDH1A1HPGDAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277502-B1 | ORGANOSILICON POLYMERS; LIQUID CRYSALS | ROLIC AG (CH) | 2001-08-21 | — | — | US | disclosed |