Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 20/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 16/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971293 | 0.89 | ADRA1A (0.64) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6787156 | 0.88 | ADRA1A (0.57) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6272493 | 0.88 | ADRA1A (0.67) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6782399 | 0.84 | ADRA1A (0.71) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6793226 | 0.82 | ADRA1A (0.64) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL7952573 | 0.81 | ADRA1A (0.74) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL7237001 | 0.80 | ADRA1A (0.60) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6785443 | 0.79 | ADRA1A (0.65) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL8595413 | 0.78 | ADRA1A (0.58) | ADRA1AADRA1DADRA1BADRA2AADRA2B | |
| SCHEMBL6786714 | 0.77 | ADRA1A (0.61) | ADRA1AADRA1DADRA1BADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268369-B1 | ALPHA SUB 1 INHIBITORS | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-07-31 | — | — | US | disclosed |