Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7956957 | 0.99 | MEN1 (0.46) | ALDH1A1MEN1KMT2ACXCR4ADORA2A | |
| SCHEMBL7953469 | 0.82 | ALDH1A1 (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7960100 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AACHEBCHE | |
| SCHEMBL7953471 | 0.82 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL7953468 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAOBHTR1A | |
| SCHEMBL7960094 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAOBHTR1A | |
| Hydrochloric Acid SCHEMBL7956973 | 0.81 | ALDH1A1 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7955380 | 0.81 | ALDH1A1 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7955381 | 0.81 | ALDH1A1 (0.46) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7954811 | 0.80 | MAOA (0.48) | ALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262078-B1 | Phenoxymethyl piperidine derivatives for the treatment of neuropathic pain | SYNTEX (U.S.A.) LLC | 2001-07-17 | — | — | US | disclosed |
| US-6110937-A | A SODIUM CHANNEL BLOCKER TREATING AS LOCAL ANESTHETICS AND IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | SYNTEX USA, INC. (US) | 2000-08-29 | — | — | US | disclosed |
| EP-0869119-A1 | Phenoxymethyl piperidine derivatives being sodium channle blockers | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-07 | — | — | EP | disclosed |
| CN-1194977-A | Phenoxymethyl piperidine derivatives | HOFFMANN LA ROCHE (CH) | 1998-10-07 | — | — | CN | disclosed |