Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948835 | 0.85 | NPY1R (0.66) | NPY1RALDH1A1TSHRHSD17B10LMNA | |
| SCHEMBL7963648 | 0.84 | NPY1R (0.53) | NPY1RALDH1A1TSHRHSD17B10HRH3 | |
| Hydrochloric Acid SCHEMBL7958663 | 0.81 | NPY1R (0.67) | NPY1RALDH1A1TSHRHSD17B10HRH3 | |
| SCHEMBL7963425 | 0.80 | NPY1R (1.00) | NPY1RALDH1A1TSHRHSD17B10HRH3 | |
| Hydrochloric Acid SCHEMBL7956797 | 0.79 | NPY1R (0.98) | NPY1RALDH1A1TSHRHSD17B10HRH3 | |
| Hydrochloric Acid SCHEMBL7956340 | 0.79 | NPY1R (0.65) | NPY1RALDH1A1TSHRHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL7948991 | 0.78 | NPY1R (0.73) | NPY1RALDH1A1TSHRHSD17B10HRH3 | |
| Hydrochloric Acid SCHEMBL7958491 | 0.77 | NPY1R (0.96) | NPY1RALDH1A1TSHRHSD17B10HRH3 | |
| SCHEMBL7960784 | 0.77 | NPY1R (0.54) | NPY1RALDH1A1TSHRHSD17B10HRH3 | |
| SCHEMBL7959181 | 0.74 | NPY1R (0.59) | NPY1RALDH1A1TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |