Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957280 | 0.84 | NPY1R (0.66) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL7956400 | 0.79 | NPY1R (0.53) | NPY1RALDH1A1HSD17B10TSHRCRHBP | |
| SCHEMBL7959114 | 0.79 | SMN1; SMN2 (0.50) | NPY1RALDH1A1CRHBPCRHR2KDM4E | |
| SCHEMBL7948835 | 0.77 | NPY1R (0.66) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL7960784 | 0.75 | NPY1R (0.54) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| SCHEMBL7948988 | 0.73 | NPY1R (0.52) | NPY1RALDH1A1HSD17B10TSHRCRHBP | |
| SCHEMBL7959181 | 0.73 | NPY1R (0.59) | NPY1RALDH1A1HSD17B10TSHRCRHBP | |
| Hydrochloric Acid SCHEMBL7958855 | 0.72 | NPY1R (0.51) | NPY1RALDH1A1HSD17B10TSHRKDM4E | |
| Hydrochloric Acid SCHEMBL7956994 | 0.71 | NPY1R (0.81) | NPY1RALDH1A1HSD17B10TSHRHRH3 | |
| SCHEMBL7963250 | 0.71 | NPY1R (0.60) | NPY1RALDH1A1HSD17B10TSHRCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |