Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RB1 | P06400 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7958855 | 0.83 | NPY1R (0.51) | NPY1RALDH1A1HSD17B10TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL7948675 | 0.78 | NPY1R (0.53) | NPY1RALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL7957280 | 0.77 | NPY1R (0.66) | NPY1RALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL7965110 | 0.77 | RAB9A (0.55) | ALDH1A1HSD17B10TSHRKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL27495505 | 0.77 | NPY1R (0.52) | NPY1RALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL7959181 | 0.76 | NPY1R (0.59) | NPY1RALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL7963648 | 0.75 | NPY1R (0.53) | NPY1RALDH1A1HSD17B10TSHRLMNA | |
| SCHEMBL7949099 | 0.74 | NPY1R (0.60) | NPY1RALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL7963250 | 0.74 | NPY1R (0.60) | NPY1RALDH1A1HSD17B10TSHRNPSR1 | |
| SCHEMBL7948835 | 0.73 | NPY1R (0.66) | NPY1RALDH1A1HSD17B10TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |