Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857590 | 0.87 | PTGER1 (0.67) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL7809016 | 0.86 | PTGER4 (0.70) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL7809010 | 0.86 | PTGER4 (0.70) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL1563532 | 0.83 | FFAR1 (0.55) | FFAR1FFAR4MAPT | |
| SCHEMBL14039572 | 0.83 | FFAR1 (0.55) | FFAR1FFAR4MAPT | |
| SCHEMBL13921688 | 0.82 | HTT (0.66) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL16319070 | 0.82 | PTGER4 (0.55) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL16319072 | 0.82 | PTGER4 (0.55) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL433576 | 0.80 | HDAC8 (0.68) | PTGER1PTGER4PTGER3PTGER2HDAC8 | |
| SCHEMBL7907911 | 0.80 | HDAC8 (0.68) | PTGER1PTGER4PTGER3PTGER2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211197-B1 | CARBOXYLIC ACID OR TETRAZOLE DERIVATES; ANALGESICS, ANTIPYRETICS, AND ANTIINFLAMMATORY AGENTS; SIDE EFFECT REDUCTION | MERCK FROSST CANADA & CO. (CA) | 2001-04-03 | — | — | US | disclosed |