Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 15/20 | 0.62 |
| ▸ | USP14 | P54578 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956872 | 0.86 | NPY1R (0.60) | NPY1RUSP14 | |
| SCHEMBL27493915 | 0.81 | NPY1R (0.74) | NPY1RUSP14TP53 | |
| SCHEMBL7959355 | 0.79 | NPY1R (0.59) | NPY1R | |
| SCHEMBL7957295 | 0.78 | NPY1R (0.87) | NPY1RUSP14 | |
| SCHEMBL7958833 | 0.78 | NPY1R (0.61) | NPY1R | |
| SCHEMBL7959646 | 0.77 | NPY1R (0.60) | NPY1RTP53 | |
| SCHEMBL7963329 | 0.77 | NPY1R (1.00) | NPY1RUSP14 | |
| Hydrochloric Acid SCHEMBL7959234 | 0.76 | NPY1R (0.98) | NPY1RUSP14 | |
| SCHEMBL7948644 | 0.75 | NPY1R (0.60) | NPY1R | |
| SCHEMBL7956831 | 0.75 | NPY1R (0.75) | NPY1RUSP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |
| CN-1173867-A | Indolyl neuropeptide Y receptor antagonists | LILLY CO ELI (US) | 1998-02-18 | — | — | CN | disclosed |