Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.57 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978537 | 0.82 | LPL (0.59) | LPLLIPGCA2CA1TRPV1 | |
| SCHEMBL13644300 | 0.82 | LPL (0.54) | LPLLIPGCA2CA1TRPV1 | |
| SCHEMBL13189266 | 0.79 | IDO1 (0.50) | CA2CA1 | |
| SCHEMBL8180214 | 0.77 | LPL (0.53) | LPLLIPGCA2CA1TRPV1 | |
| SCHEMBL104085 | 0.77 | LPL (0.58) | LPLLIPGCA2CA1TRPV1 | |
| SCHEMBL150306 | 0.73 | LPL (1.00) | LPLLIPGCA2CA1TRPV1 | |
| SCHEMBL10091444 | 0.72 | CYP3A4 (0.52) | — | |
| SCHEMBL7706546 | 0.72 | TRPA1 (0.39) | TSHR | |
| SCHEMBL12626829 | 0.72 | IDO1 (0.52) | — | |
| SCHEMBL12824780 | 0.72 | TSHR (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137499-A1 | INHIBITORS OF HISTONE DEACETYLASE | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009137462-A2 | METHODS FOR TREATING COGNITIVE DISORDERS USING INHIBITORS OF HISTONE DEACETYLASE | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2008055068-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2008-05-08 | — | — | WO | disclosed |