Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12525140 | 0.76 | ALDH1A1 (0.41) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL2145229 | 0.76 | CYP2C19 (0.42) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL31496870 | 0.76 | CYP2C19 (0.36) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11856775 | 0.73 | CYP2C19 (0.36) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11971064 | 0.71 | CYP2C19 (0.38) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11853635 | 0.71 | CYP2C19 (0.35) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL11854529 | 0.71 | LMNA (0.44) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL16821986 | 0.70 | CYP2C19 (0.35) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL2144561 | 0.69 | ALDH1A1 (0.36) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A | |
| SCHEMBL1564269 | 0.68 | HRH3 (0.46) | CYP2C19YTHDC1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329523-B1 | FOR ANTIBACTERIAL PHARMACEUTICAL USE, USEFUL FOR IDENTIFYING METAL CHELATING SPECIES FOR ?HEAVY METAL? THERAPY; IMAGING AGENTS | ISIS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |