Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.57 |
| ▸ | TDO2 | P48775 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | USP8 | P40818 | 3/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808047 | 0.76 | IDO1 (0.79) | IDO1TDO2ALDH1A1POLB | |
| SCHEMBL7805902 | 0.75 | IDO1 (0.63) | IDO1TDO2ALDH1A1NPC1MAPT | |
| SCHEMBL8960660 | 0.74 | CYP1A2 (0.49) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7816954 | 0.73 | IDO1 (1.00) | IDO1TDO2ALDH1A1NPC1MAPT | |
| SCHEMBL7816362 | 0.73 | IDO1 (0.55) | IDO1TDO2ALDH1A1NPC1MAPT | |
| SCHEMBL7811800 | 0.72 | IDO1 (0.62) | IDO1TDO2ALDH1A1RXFP1NPC1 | |
| SCHEMBL7805767 | 0.72 | IDO1 (0.71) | IDO1TDO2ALDH1A1NPC1MAPT | |
| SCHEMBL7974992 | 0.72 | IDO1 (1.00) | IDO1TDO2ALDH1A1NPC1MAPT | |
| SCHEMBL7815259 | 0.71 | IDO1 (0.63) | IDO1TDO2ALDH1A1RAB9APTPRC | |
| SCHEMBL7816639 | 0.71 | IDO1 (0.57) | IDO1TDO2ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262095-B1 | TREATMENT OF ILLNESS ASSOCIATED WITH AN ALTERATION IN VENOUS FUNCTION AND/OR INFLAMMATORY EDEMA | LABORATOIRE INNOTHERA (FR) | 2001-07-17 | — | — | US | disclosed |