Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572799 | 0.83 | LMNA (0.54) | LMNATAAR1KDM4EL3MBTL1SLC6A3 | |
| SCHEMBL9172184 | 0.79 | TRPA1 (0.59) | LMNAHTR2ATAAR1KDM4ECHRM2 | |
| SCHEMBL9737526 | 0.79 | LMNA (0.48) | LMNAHTR2ATAAR1KDM4EL3MBTL1 | |
| SCHEMBL7963200 | 0.78 | HRH1 (0.50) | LMNAHTR2ATAAR1KDM4EL3MBTL1 | |
| SCHEMBL9838705 | 0.78 | HTR2A (0.58) | HTR2ATAAR1GRM2GRM3HRH1 | |
| SCHEMBL5572359 | 0.77 | HTR2A (0.46) | HTR2ATAAR1GRM2GRM3HRH1 | |
| SCHEMBL7962883 | 0.76 | LMNA (0.41) | LMNAHTR2ATAAR1KDM4EL3MBTL1 | |
| SCHEMBL3980450 | 0.75 | GRM2 (0.47) | LMNAHTR2ATAAR1KDM4EL3MBTL1 | |
| SCHEMBL21141876 | 0.75 | GRM2 (0.52) | LMNAHTR2ATAAR1KDM4EGRM2 | |
| SCHEMBL108142 | 0.75 | CYP2C9 (0.50) | LMNAHTR2AKDM4EHRH1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103403057-B | The manufacture method of polyester and fluorine-containing di-carboxylic acid ester cpds | ASAHI GLASS CO.,LTD. (JP) | 2016-01-20 | — | — | CN | disclosed |
| CN-102958976-B | Continuous process for the production of branched polycarbonate | ASAHI KASEI CHEMICALS CORP | 2014-11-26 | — | — | CN | disclosed |
| CN-103403057-A | Method for producing polyester, and fluorine-containing dicarboxylic acid ester compound | ASAHI GLASS CO LTD | 2013-11-20 | — | — | CN | disclosed |
| CN-102958976-A | Continuous process for the production of branched polycarbonate | ASAHI KASEI CHEMICALS CORP (JP) | 2013-03-06 | — | — | CN | disclosed |
| CN-1160395-C | method and polymerization apparatus for producing aromatic polycarbonate | � ��ʽ���� | 2004-08-04 | — | — | CN | disclosed |
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| CN-1286713-A | method and polymerization apparatus for producing aromatic polycarbonate | ASAHI CHEMICAL IND (JP) | 2001-03-07 | — | — | CN | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |