Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | ECE1 | P42892 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958217 | 1.00 | PPARA (0.40) | PPARAECE1FFAR1PPARGDRD2 | |
| SCHEMBL23771659 | 1.00 | PPARA (0.40) | PPARAECE1FFAR1PPARGDRD2 | |
| SCHEMBL22036215 | 1.00 | PPARA (0.40) | PPARAECE1FFAR1PPARGDRD2 | |
| SCHEMBL22035427 | 1.00 | PPARA (0.40) | PPARAECE1FFAR1PPARGDRD2 | |
| SCHEMBL1915907 | 1.00 | PPARA (0.40) | PPARAECE1FFAR1PPARGDRD2 | |
| SCHEMBL23699239 | 0.82 | DRD2 (0.45) | PPARAECE1DRD2 | |
| SCHEMBL7956194 | 0.82 | CYP1A2 (0.53) | PPARAECE1FFAR1PPARG | |
| SCHEMBL7956197 | 0.82 | CYP1A2 (0.53) | PPARAECE1FFAR1PPARG | |
| SCHEMBL23751360 | 0.81 | FFAR1 (0.42) | PPARAFFAR1PPARG | |
| SCHEMBL22036314 | 0.81 | FFAR1 (0.42) | PPARAFFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262060-B1 | TREATMENT OF HYPERGLYCAEMIA, DIABETES, OBESITY OR INFLAMMATION | SANOFI-SYNTHELABO (FR) | 2001-07-17 | — | — | US | disclosed |