Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 5/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699407 | 0.93 | DRD2 (0.44) | DRD2ACESYKECE1 | |
| SCHEMBL23699401 | 0.90 | DRD2 (0.44) | DRD2ACESYKMTNR1AMTNR1B | |
| SCHEMBL1915907 | 0.82 | PPARA (0.40) | DRD2ECE1PPARA | |
| SCHEMBL22035427 | 0.82 | PPARA (0.40) | DRD2ECE1PPARA | |
| SCHEMBL22036215 | 0.82 | PPARA (0.40) | DRD2ECE1PPARA | |
| SCHEMBL7958486 | 0.82 | PPARA (0.40) | DRD2ECE1PPARA | |
| SCHEMBL23771659 | 0.82 | PPARA (0.40) | DRD2ECE1PPARA | |
| SCHEMBL7958217 | 0.82 | PPARA (0.40) | DRD2ECE1PPARA | |
| SCHEMBL14453238 | 0.80 | IDO1 (0.43) | DRD2IDO1SCN9APPARA | |
| SCHEMBL31757939 | 0.80 | IDO1 (0.43) | DRD2IDO1SCN9APPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |