Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948851 | 0.92 | CYP24A1 (0.53) | ALDH1A1MCL1TBXA2RTBXAS1CYP24A1 | |
| SCHEMBL7957937 | 0.86 | MCL1 (0.50) | ALDH1A1MCL1TDP1HTR6PPARG | |
| SCHEMBL7956866 | 0.83 | MCL1 (0.48) | ALDH1A1MCL1TDP1HTR6PPARG | |
| SCHEMBL7956741 | 0.79 | MCL1 (0.52) | ALDH1A1MCL1TDP1HTR6PPARG | |
| SCHEMBL7959506 | 0.79 | MCL1 (0.60) | ALDH1A1MCL1TDP1HTR6PPARG | |
| SCHEMBL7960155 | 0.78 | MCL1 (0.59) | ALDH1A1MCL1TDP1HTR6PPARG | |
| SCHEMBL7959220 | 0.74 | MCL1 (0.59) | ALDH1A1MCL1TDP1HTR6PPARG | |
| SCHEMBL7956906 | 0.74 | MCL1 (0.59) | ALDH1A1MCL1TBXA2RTDP1PPARG | |
| SCHEMBL7959081 | 0.73 | MCL1 (0.53) | ALDH1A1MCL1TDP1HTR6PPARG | |
| SCHEMBL7948387 | 0.73 | MCL1 (0.55) | ALDH1A1MCL1TDP1HTR6PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |