SCHEMBL7958565

SCHEMBL7958565

N#C[CH]c1cncc(Cl)c1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.37
CYP11B2 P19099 2/20 0.37
HCAR2 Q8TDS4 1/20 0.35
MAPT P10636 1/20 0.34
CLK1 P49759 1/20 0.31
DYRK1A Q13627 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989986 0.71
SCHEMBL335671 0.71
SCHEMBL14844098 0.71
SCHEMBL30966540 0.71
Water SCHEMBL28044737 0.71
SCHEMBL7968962 0.71 CYP11B2 (0.38) CYP11B1CYP11B2MAPT
Water SCHEMBL28044696 0.69 HCAR2 (0.48) CYP11B1CYP11B2HCAR2CHRNB2CHRNA4
SCHEMBL8438588 0.68 HCAR2 (0.36) HCAR2CHRNB2CHRNA4
SCHEMBL8436245 0.68 HCAR2 (0.36) HCAR2CHRNB2CHRNA4
SCHEMBL7216919 0.68 CHRM5 (0.52) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed