Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968716 | 0.77 | POLB (0.41) | CYP11B2CYP11B1MAPTALDH1A1KDM4E | |
| SCHEMBL8436212 | 0.77 | CYP11B2 (0.39) | CYP11B2CYP11B1MAOBMAPTCYP19A1 | |
| SCHEMBL5253887 | 0.75 | ALDH1A1 (0.50) | MAOBMAOAMAPTALDH1A1KDM4E | |
| SCHEMBL7975159 | 0.73 | AHR (0.53) | MAPTALDH1A1KDM4ELMNACYP19A1 | |
| SCHEMBL8491445 | 0.73 | RELA (0.42) | MAOBMAPTLMNAGAA | |
| SCHEMBL7958255 | 0.72 | NPC1 (0.40) | MAPTALDH1A1L3MBTL1 | |
| SCHEMBL565871 | 0.72 | — | — | |
| SCHEMBL7971923 | 0.72 | CHRM5 (0.47) | MAOBMAOAMAPTFBP1 | |
| SCHEMBL7501598 | 0.71 | NPC1 (0.46) | MAOBMAOAMAPTALDH1A1LMNA | |
| SCHEMBL7958565 | 0.71 | CYP11B1 (0.37) | CYP11B2CYP11B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |