Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958841 | 0.75 | NPY5R (0.39) | NPY5RALDH1A1HPGD | |
| SCHEMBL5774307 | 0.71 | MEN1 (0.47) | NPY5RGFERPDE10A | |
| SCHEMBL112929 | 0.67 | HTT (0.46) | ALDH1A1HPGDPDE10A | |
| SCHEMBL21159616 | 0.64 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL29619235 | 0.62 | PDE10A (0.49) | ALDH1A1HPGDPDE10A | |
| SCHEMBL9830230 | 0.62 | KMT2A (0.37) | ALDH1A1 | |
| SCHEMBL116212 | 0.62 | HTT (0.37) | NPY5RALDH1A1PDE10A | |
| SCHEMBL82728 | 0.61 | JAK3 (0.40) | NPY5RALDH1A1HPGDGFER | |
| SCHEMBL19917147 | 0.61 | PDE10A (0.48) | ALDH1A1HPGDPDE10A | |
| SCHEMBL27899278 | 0.60 | ADORA2A (0.62) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187777-B1 | PYRROLO(3,2-D)PYRIMIDINE DERIVATIVES; NEUROPEPTIDE Y AND CORTICOTROPIN RELEASING FACTOR MODULATORS; DIETETICS; ANTIDIABETIC, ANTIINFLAMMATORY, AND ANTITUMOR AGENTS | AMGEN INC. | 2001-02-13 | — | — | US | disclosed |