Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869184 | 0.87 | TNK2 (0.40) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL4390019 | 0.87 | TNK2 (0.40) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL3500438 | 0.86 | TNK2 (0.44) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL7231881 | 0.84 | KMT2A (0.40) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL20032688 | 0.84 | MEN1 (0.40) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL7774785 | 0.84 | KMT2A (0.40) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL19389542 | 0.81 | TNK2 (0.40) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL4377518 | 0.81 | TNK2 (0.36) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL9875684 | 0.81 | HSD11B1 (0.39) | TNK2MEN1KMT2ADHFRHSD11B1 | |
| SCHEMBL15869195 | 0.80 | FFAR1 (0.39) | TNK2MEN1KMT2ADHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |