Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875684 | 0.88 | HSD11B1 (0.39) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL15869184 | 0.87 | TNK2 (0.40) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL4390019 | 0.87 | TNK2 (0.40) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL3500438 | 0.86 | TNK2 (0.44) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL7774785 | 0.84 | KMT2A (0.40) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL7231881 | 0.84 | KMT2A (0.40) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL7958837 | 0.84 | TNK2 (0.38) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL27984097 | 0.84 | MEN1 (0.39) | MEN1KMT2ATNK2HSD11B1DHFR | |
| SCHEMBL7860591 | 0.82 | MEN1 (0.45) | MEN1KMT2ATNK2SLC6A3NPC1 | |
| SCHEMBL15093765 | 0.81 | MEN1 (0.43) | MEN1KMT2ATNK2HSD11B1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9939555-B2 | Cinnamic acid derivative, polymer thereof, and liquid crystal alignment layer comprising cured product thereof | DIC CORPORATION (JP) | 2018-04-10 | — | — | US | disclosed |