Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963164 | 0.93 | NPY1R (1.00) | NPY1RSMN1; SMN2KMT2AHRH3 | |
| SCHEMBL7956905 | 0.89 | NPY1R (0.83) | NPY1RKMT2A | |
| SCHEMBL7949187 | 0.86 | NPY1R (0.79) | NPY1RSMN1; SMN2KMT2AKDM4EHRH3 | |
| SCHEMBL7957295 | 0.86 | NPY1R (0.87) | NPY1RSMN1; SMN2KMT2A | |
| SCHEMBL7956724 | 0.84 | NPY1R (0.75) | NPY1RKMT2ATP53 | |
| SCHEMBL7963219 | 0.84 | NPY1R (0.75) | NPY1RSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL7957128 | 0.84 | NPY1R (0.84) | NPY1RSMN1; SMN2HRH3 | |
| SCHEMBL7957137 | 0.84 | NPY1R (0.69) | NPY1RKMT2ATACR1KDM4EHRH3 | |
| SCHEMBL7958925 | 0.83 | NPY1R (0.71) | NPY1RKMT2AKDM4E | |
| SCHEMBL7958736 | 0.83 | NPY1R (0.71) | NPY1RSMN1; SMN2KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245761-B1 | NERVOUS SYSTEM, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2001-06-12 | — | — | US | disclosed |