Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.54 |
| ▸ | MMP3 | P08254 | 5/20 | 0.54 |
| ▸ | MMP2 | P08253 | 5/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22120085 | 0.98 | HRH3 (0.57) | MAPTALDH1A1HRH3MMP3MMP2 | |
| SCHEMBL17274247 | 0.98 | HRH3 (0.57) | MAPTALDH1A1HRH3MMP3MMP2 | |
| SCHEMBL5522292 | 0.98 | HRH3 (0.57) | MAPTALDH1A1HRH3MMP3MMP2 | |
| SCHEMBL14665672 | 0.98 | HRH3 (0.57) | MAPTALDH1A1HRH3MMP3MMP2 | |
| SCHEMBL9786700 | 0.94 | MMP3 (0.61) | MAPTALDH1A1HRH3MMP3MMP2 | |
| SCHEMBL1618099 | 0.94 | ALDH1A1 (0.56) | MAPTALDH1A1HRH3MMP3MMP2 | |
| SCHEMBL9169148 | 0.93 | HDAC1 (0.62) | ALDH1A1HRH3MMP3MMP2HDAC1 | |
| SCHEMBL4594927 | 0.93 | HDAC1 (0.62) | ALDH1A1HRH3MMP3MMP2HDAC1 | |
| SCHEMBL5091525 | 0.93 | HDAC1 (0.62) | ALDH1A1HRH3MMP3MMP2HDAC1 | |
| SCHEMBL5097477 | 0.93 | HDAC1 (0.62) | ALDH1A1HRH3MMP3MMP2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440251-B | Method for photo/nickel concerted catalysis of monoarylation diol | 陕西师范大学 | 2021-01-01 | — | — | CN | disclosed |
| US-6291475-B1 | 3,7-DIAZABICYCLO(3.3.1)NONANE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-09-18 | — | — | US | disclosed |
| EP-1047695-A1 | NOVEL BISPIDINE ANTIARRHYTHMIC COMPOUNDS | AstraZeneca AB (SE) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999031100-A1 | NOVEL BISPIDINE ANTIARRHYTHMIC COMPOUNDS | ASTRAZENECA AB (SE) | 1999-06-24 | — | — | WO | disclosed |
| CN-1039816-A | Primary polyether active hydrogen compounds and preparation method thereof | DOW CHEMICAL CO (US) | 1990-02-21 | — | — | CN | disclosed |
| US-4720581-A | ANTISEPTICS, PRESERVATIVES | SANOFI (FR) | 1988-01-19 | — | — | US | disclosed |