Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL9679981 | 0.75 | AKR1C3 (0.59) | IDO1ALDH1A1MAPTAKR1C3AKR1C1 | |
| SCHEMBL9380468 | 0.75 | ALOX5 (0.54) | ALOX5ALDH1A1MAPTKDM4E | |
| SCHEMBL9380470 | 0.75 | ALOX5 (0.54) | ALOX5ALDH1A1MAPTKDM4E | |
| SCHEMBL28856478 | 0.74 | IDO1 (0.48) | CYP2C9IDO1ALDH1A1LMNAMAPT | |
| SCHEMBL7975742 | 0.74 | ALOX5 (0.50) | ALOX5AKR1C3AKR1C1 | |
| SCHEMBL7975745 | 0.74 | ALOX5 (0.50) | ALOX5AKR1C3AKR1C1 | |
| SCHEMBL7973281 | 0.73 | AKR1C3 (0.46) | ALOX5AKR1C3AKR1C1KDM4ENPC1 | |
| SCHEMBL7969786 | 0.73 | AKR1C3 (0.46) | ALOX5AKR1C3AKR1C1KDM4ENPC1 | |
| SCHEMBL7969789 | 0.73 | AKR1C3 (0.46) | ALOX5AKR1C3AKR1C1KDM4ENPC1 | |
| SCHEMBL17025385 | 0.72 | ESR2 (0.70) | CYP2C9IDO1AKR1C3AKR1C1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291520-B1 | INHIBIT THE ENZYME LIPOXYGENASE; TREATMENT OR ALLEVIATION OF INFLAMMATORY DISEASES, ALLERGIC CONDITIONS AND CARDIOVASCULAR DISEASES | PFIZER | 2001-09-18 | — | — | US | disclosed |